Anticancer and antioxidant activity of ethanolic extract of Clove (Syzygium aromaticum) on oral squamous cell carcinoma cell lines (KB cell lines)- An In-vitro study

Cloves (Syzygium aromaticum) as been used traditional medicine for many years and they possess antibacterial, antifungal antiviral properties. Clove is known its anticancer property on various cancer cell lines well established, but effect OSCC less known. Aim of the study was to determine antioxidant Syzygium aromaticum extract (KB lines) compare same with normal mouse fibroblasts (L292 lines). KB L292 were commercially obtained. obtained from local market ethanolic (EC) clove prepared. Anticancer activity assessed by MTT, neutral red, DAPI Double staining assay carried out FRAP, PM DPPH assay. The EC increased increase in concentration a dose dependent manner. Both MTT Neutral Red showed death clove. when treated comparable standard drug This vitro demonstrates effective compared control. However, further studies are be conducted order characterize other potential antitumor components clove, so that it can therapeutic agent treating oral carcinoma.